Leser–Trélat sign
Leser–Trélat sign
Onset of multiple seborrheic keratoses.
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Readers' pathsAug 2026 – Oct 2026
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Seborrheic keratosis
Benign skin tumor originating in keratocytes.
25%
Acanthosis nigricans
Darkening of the skin around bodily folds.
7.2%
Cowden syndrome
Familial syndrome causing hamartomas and cancers.
7.1%
Palmoplantar keratoderma
Abnormal thickening of skin in the palms or soles.
3.5%
Angioma
Benign tumors derived from cells composing or surrounding blood or lymph vessels.
3.3%
Colorectal cancer
Cancer of the colon or rectum.
1.9%
Neoplasm
Tumor or other abnormal growth of tissue.
1.4%
Ulysse Trélat
French surgeon.
0.73%
Adenocarcinoma
Cancer of epithelial cells with glandular origin or characteristics.
0.67%
Malignancy
Tendency of a medical condition to become progressively worse.
0.61%
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